Investigation of the level of response to botulinum-a toxin injection treatment in patient with lower urinary system disfonction
Sencer Sağlam1
, Bilge Türedi Sezer2, Mehmet Uğur Yılmaz1, Nizamettin Kılıç1, Mehmet Emin Balkan1
1Uludağ Üniversitesi Tıp Fakültesi Çocuk Cerrahisi Anabilim Dalı, Bursa-TÜRKİYE
2Konya Şehir Hastanesi, Konya-TÜRKİYE
Keywords: Lower urinary system dysfunction, bladder elastography, Botulinum Toxin-A injection
Abstract
Objective: In our study, we aimed to examine the response level to treatment with different diagnostic methods in selected patients who were treated bladder with Botulinum Toxin-A (BTA) injection due to lower urinary system dysfunction.
Method: In this prospective study; injected cases in pre-op and post-op period; urodynamic study was subjected to various diagnostic methods such as Voiding Disorder Symptom Scoring (VDSS) and Bladder Elastography (ME). In addition, a control group consisting of urologically healthy patients was formed for ME.
Results: Significant changes were found in functional bladder capacity and bladder compliance values and VDSS values in the pre-op and post-op urodynamic studies of the patients who received BTA injection. Similar changes were not reflected in ME parameters.
Conclusion: BTA injection into the bladder in cases diagnosed with lower urinary system dysfunction; It is an effective treatment method. Although this efficacy can be demonstrated by urodynamic studies and various symptom scorings, further standardization studies are needed for ME.
Cite as: Sağlam S, Kılıç N, Türedi Sezer B, Yılmaz MU, Balkan ME. Alt üriner system disfonksiyonu olan olgularda botulinum-a toksini enjeksiyonu tedavisine yanıt düzeyinin araştırılması. Coc Cer Derg/Turkish J Ped Surg 2022;36(3): 28-35. doi: 10.29228/JTAPS.58154