Demographic and clinicopathological features and long-term results of pediatric cases diagnosed with pilomatrixoma
Aziz Serhat Baykara1, Bahattin Erdoğan2
1Department of Pediatric Surgery, University of Health Sciences, Eskişehir City Hospital, Eskişehir, Türkiye
2Department of Pathology, University of Health Sciences, Eskişehir City Hospital, Eskişehir, Türkiye
Keywords: Childhood tumors, pilomatrixoma, surgical excision.
Abstract
Objectives: In this study, we present our experience with pilomatrixoma in pediatric patients.
Patients and methods: Between January 2013 and January 2023, a total of 86 children (29 males, 57 females; mean age: 10.8±4.2 years; range, 1 to 18 years) who were diagnosed with pilomatrixoma based on histopathological examination of excisional biopsies were included. Demographic characteristics of the patients, symptoms, location of lesions, radiological imaging results and pathology reports were obtained from the medical records.
Results: The number of patients under the age of 10 diagnosed with pilomatrixoma was 29 (33.7%), while there were 57 (66.2%) patients between 10 and 18 years of age. Eighty-three (88.3%) of our cases were in the form of a single nodule, and three (11.6%) were in the form of multiple nodules. In terms of tumor localization, 38 (42.6%) were located in the head and neck region, 29 (32.5%) in the upper extremities, 14 (15.7%) in the trunk and eight (8.9%) in the lower extremities. One patient (1.1%) was reoperated due to recurrence during postoperative follow-up.
Conclusion: Pilomatrixoma should be surgically excised, as it can be confused with other subcutaneous tumors usually seen in children and adolescents. Its ability to show malignant transformation over time should not be overlooked.
Citation: Baykara AS, Erdoğan B. Demographic and clinicopathological features and long-term results of pediatric cases diagnosed with pilomatrixoma. Turkish J Ped Surg 2023;37(3):79-83. doi: 10.62114/JTAPS.2023.71026.
The study protocol was approved by the University of Health Sciences, Eskişehir City Hospital, Clinical Research Ethics Committee (date: 20.06.2023, no: ESH/GOEK 2023/33). The study was conducted in accordance with the principles of the Declaration of Helsinki.
A written informed consent was obtained from the patients and/or parents of the patients.
Data Sharing Statement:
The data that support the findings of this study are available from the corresponding author upon reasonable request.
Idea/concept, control/ supervision, data collection and/or processing, references and fundings, materials: A.S.B., B.E.; Design, analysis and/or interpretation, literature review, writing the article, critical review: A.S.B.
The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.
The authors received no financial support for the research and/or authorship of this article.